Xelpros™ is a novel, translucent, almost colorless, BAK-free Latanoprost Ophthalmic Emulsion developed with Swollen Micelle Microemulsion™ (SMM) Technology.
Prostaglandin analogues such as Latanoprost are the first line treatment for open-angle glaucoma or ocular hypertension and form the largest drug class.
The currently marketed Latanoprost Eye Drops contain Benzalkonium Chloride (BAK). BAK is a common preservative in topical ocular preparations; however, prolonged use may lead to deleterious effects on the ocular surface, affecting quality of life and reducing adherence to treatment and overall outcomes. Use of BAK has been associated with the increased risk of developing OSD1. Patients with OSD, experience symptoms of ocular discomfort like dryness, burning or stinging, itching, irritation, tearing, etc. These symptoms can have a substantial impact on a patient’s quality of life and potentially lead to reduced adherence with treatment regimens.
In a head to head comparative study in Glaucoma patients, Xelpros™ was found to be as efficacious and as safe as Xalatan.
Xelpros™ offers a novel and BAK free treatment option for patients with open-angle glaucoma or ocular hypertension. Xelpros™, unlike other marketed products of Latanoprost, is stable at room temperature and does not require storage at 2-80C.
Xelpros™ is now approved by USFDA and is licensed for US market to a subsidiary of Sun Pharmaceutical Industries Limited.